Legume consumption shown to improve blood glucose control and ...

by John Phillip

(NaturalNews) Poor blood glucose control is a leading indicator of pending chronic illness, as excess sugars combine with proteins and fats to create advanced glycation end products (AGE?s) that damage the lining of arteries throughout the body and block blood flow in the smallest capillaries of the eyes, kidneys and extremities. A number of natural foods and compounds have been validated to block the formation of damaging AGE?s. Among them are resveratrol, carnosine and the consumption of many varieties of nuts and seeds.

A research team from the University of Toronto in Canada, publishing in the Archives of Internal Medicine have found that eating more legumes (such as beans, chickpeas or lentils) as part of a low-glycemic index diet appears to improve glycemic control and reduce estimated coronary heart disease risk in patients with Type II diabetes mellitus. In prior research works, many low glycemic index foods have been associated with improvements in the industry standard hemoglobin A1C blood test that determines blood sugar levels over the past 90 to 120 days.

Increasing legume consumption and eliminating processed foods lowers cardiovascular disease risks
Lead researcher, Dr. David Jenkins conducted a randomized, controlled study of 121 patients previously diagnosed with Type II diabetes to test the effect of eating more legumes on glycemic control, serum blood lipid levels and blood pressure. Participants were divided into two groups to receive either a low-glycemic diet that emphasized eating at least one cup of legumes each day or to increase consumption of whole wheat carbohydrates (known to boost blood glucose levels in a similar manner to eating table sugar) for a period of three months.

The study team used changes in hemoglobin A1C to determine overall heart disease risk. The results demonstrated that A1C was lowered by a statistically significant factor of .5 in the legume-consuming group and .3 among the wheat eaters. Heart disease risk was reduced by .8 percent among the legume group, largely due to reductions in systolic blood pressure readings. The scientists concluded ?Legume consumption of approximately 190 g per day (one cup) seems to contribute usefully to a low-GI diet and reduce CHD risk through a reduction in BP.?

The result of eating a relatively small amount of legumes every day are not dramatic, yet do provide a small heart disease risk reduction. This study provides one example of how altering diet impacts chronic disease risk. Much greater health improvements are realized by eliminating hydrogenated and fried foods, limiting refined carbohydrates and eliminating sugar from the diet. Adding healthy options including legumes, fresh fruits and vegetables, nuts and seeds will optimize health and dramatically lower risk of cardiovascular disease.

Sources for this article include:

http://archinte.jamanetwork.com/article.aspx?articleid=1384247

http://www.sciencedaily.com/releases/2012/10/121022162546.htm

http://www.medpagetoday.com/PrimaryCare/DietNutrition/35491

http://www.medicalnewstoday.com/articles/251882.php

About the author:
John Phillip is a Certified Nutritional Consultant and Health Researcher and Author who writes regularly on the cutting edge use of diet, lifestyle modifications and targeted supplementation to enhance and improve the quality and length of life. John is the author of ?Your Healthy Weight Loss Plan?, a comprehensive EBook explaining how to use Diet, Exercise, Mind and Targeted Supplementation to achieve your weight loss goal. Visit My Optimal Health Resource to continue reading the latest health news updates, and to download your Free 48 page copy of ?Your Healthy Weight Loss Plan?.

Source: http://www.ironmagazine.com/blog/2012/legume-consumption-shown-to-improve-blood-glucose-control-and-lower-heart-disease-risk/

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Obama Vs. Romney Wash. Post-ABC Poll: November 2 - Business ...

AP

Republican nominee Mitt Romney flew back into the lead in the Washington Post/ABC News tracking poll Friday. He now leads President Barack Obama 49-48, a flip from Thursday's 49-48 Obama lead.

This tracking poll has been extremely close as of late. As the Post notes, it's the eighth consecutive day with both candidates at either 49 or 48 percent. The poll comes after Obama had pulled into a tie in the Ramussen daily tracking poll, a survey in which he had been reliably trailing lately.

A few interesting internal numbers from the poll:

• Obama's approval rating stands at an even 50 percent, right at the "safe" level that typically precedes an incumbent's re-election.
• Just 43 percent of likely voters say the country is on the right track, compared with 55 percent who think it's on the wrong track. Among independents, it's an even worse 38-59 split.
• Romney leads, 50-46, on handling the economy.
• Obama leads, 50-45, on having an understanding of people's economic problems.
• Obama, surprisingly, has the enthusiasm edge. Sixty-six percent of his supporters say they're "very enthusiastic" ? only 62 percent say the same for Romney.

Source: http://www.businessinsider.com/obama-vs-romney-wash-post-abc-poll-november-2-2012-11

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Government To Review Procedure To Expedite Registration Of ...

KUANTAN ? The government is to facilitate and expedite the registration of nurseries without the need for the prior approval of technical agencies so long as they meet the minimum standard set by the Social Welfare Department, Prime Minister Datuk Seri Najib Tun Razak said today.

Najib, who is also minister of women, family and community development, said the review of the registration procedure was most necessary to ensure that more nurseries could be opened in the future.

?So long as a nursery meets the standard requirements, its registration can be approved so that it can start operating,? he said at the launch of the Astro Kasih Knowledge Zone programme at the Sultanah Hajah Kalsom Children?s Home in Penor, near here.

Nursery operators must now obtain the approval of the technical agencies, such as the local authority, health department and fire & rescue department before the nurseries can registered by the social welfare department.

Najib said that under the new initiative, 372 new nurseries could be registered, bring their total number to 1,767.

?All these nurseries will benefit almost 53,000 children throughout the country who will receive quality and wholesome early childhood education and care,? he said.

Also present at the event were Najib?s wife, Datin Seri Rosmah Mansor; Pahang Menteri Besar Datuk Seri Adnan Yaakob; Deputy Women, Family and Community Development Minister Senator Heng Seai Kie and Astro chairman Tun Zaki Tun Azmi.

Najib also said that the government allocated RM10 million for providers of early childhood education centres to open new nurseries of quality so that the other children were given the opportunity to develop just like the more fortunate.

?Through this initiative, the government expects to be able to help set up 1,000 new nurseries at the rate of RM10,000 per nursery to benefit almost 30,000 children beginning next year,? he said.

He also said that under the Astro Kasih Knowledge Zone programme, Astro provided a B.yond decoder and its installation and a monthly subscription of a family package free of charge to all welfare homes registered with the social welfare department.

Astro would also set up a reading corner with reading material at 24 children?s welfare centres throughout the country, he added. ? BERNAMA

Related posts:

Source: http://mynewshub.my/eng/2012/11/government-to-review-procedure-to-expedite-registration-of-nurseries-says-najib/

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Video: Anger simmers in Staten Island

>>> good evening, tonight an entire region of the country remains in the grip of a crisis, large areas are paralyzed, people are suffering and the death toll is rising. and patience is already running out because some of the areas of the civilized society are not working. put it this way, in new york city , people can't find gasoline, and some went to find food from dumpsters from the sto stores, because they have no power or water, and what they have is still good, although it needed to be thrown out. and you will hear the memory of katrina more and more in the coming days. like katrina, three days out, we're still learning about places receiving very little help and attention, like staten island , ann curry has more.

>> reporter: brian, good evening to you, that is right, the outrage boiled over here in staten island , because more than three days after the hurricane here, people from the close-knit community, accused them of responding much slower here than to the richer parts of the city.

>> every single person on this block lost everything.

>> reporter: staten island has had enough.

>> we just want everyone to know that we are hurting down here and we need help, immediately.

>> reporter: residents here are asking why hasn't more help arrived?

>> i think we're not getting more attention, because we are a working class neighborhood. and it is kind of like fend for yourself kind of thing.

>> reporter: on the streets hit with debris, where the death toll has gone up to at least 19, today, the fury was seen live on television.

>> but you need to come here and help us, we need help, please.

>> reporter: they call it a disgrace.

>> they're nowhere to be found. so all the american red cross , all of these people making these big salaries, these big salaries, should be out there on the front line, i am despite disappointed.

>> reporter: meanwhile, they're questioning the city's priority.

>> the city is talking about getting water out of the battery tunnel , and preparing for a marathon.

>> we're pulling bodies out of the water. you see the disconnect here?

>> reporter: today, the new york police and fire department were still going house to house to account for everyone who did not follow the mandatory evacuation order. and you look me straight in the eye and say the response was not disproportionate, from the richer.

>> absolutely not, there are fema task forces assigned here and helping with the searches.

>> we are in the community talking to the residents that have been affected. and we're urging everybody to register with fema.

>> i never planned to leave here, i thought i would stay here.

>> reporter: she didn't lose members of her family but did lose almost everything else.

>> i want to go home, but there is no home, i can't go home, and it is killing me, i want to go home to my house.

>> reporter: at 62 and a grandmother, she is trying to find traces of her life.

>> this is the only wedding photograph of my mom.

>> reporter: a moment of joy, as the water on staten island recedes amid the widespread desperation and grief. and adding to that, two children were found today, the bodies missing. we're looking at the outrage on staten island , and waiting for a response.

>> ann curry , for people not familiar with the city, you can see where ann is on top of 30 rockefeller plaza , and a lot of people are re-thinking holding the new york city marathon, and

Source: http://video.msnbc.msn.com/nightly-news/49650027/

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At the end, Romney, Obama spar over voter revenge

Republican presidential candidate and former Massachusetts Gov. Mitt Romney picks up Levi Vandenberg, five months, of Dover, N.H., as he greets a ropeline of supporters as he campaigns at Portsmouth International Airport, in Newington, N.H., Saturday, Nov. 3, 2012. (AP Photo/Charles Dharapak)

Republican presidential candidate and former Massachusetts Gov. Mitt Romney picks up Levi Vandenberg, five months, of Dover, N.H., as he greets a ropeline of supporters as he campaigns at Portsmouth International Airport, in Newington, N.H., Saturday, Nov. 3, 2012. (AP Photo/Charles Dharapak)

President Barack Obama speaks to supporters during a campaign event at Mentor High School, Saturday, Nov. 3, 2012, in Mentor, Ohio. (AP Photo/Pablo Martinez Monsivais)

President Barack Obama visits the Federal Emergency Management Agency (FEMA) for an update on the recovery from Hurricane Sandy that hit New York and New Jersey especially hard earlier this week, Saturday morning, Nov. 3, 2012, in Washington. He is flanked by FEMA chief Craig Fugate, left, and Homeland Security Secretary Janet Napolitano, right. Next to Napolitano is Defense Secretary Leon Panetta and Treasury Secretary Timothy Geithner, far right. (AP Photo/J. Scott Applewhite)

The crowd cheers as Republican presidential candidate and former Massachusetts Gov. Mitt Romney and wife Ann Romney campaign at Portsmouth International Airport, in Newington, N.H., Saturday, Nov. 3, 2012. (AP Photo/Charles Dharapak)

Ann Romney, wife of Republican presidential candidate and former Massachusetts Gov. Mitt Romney, hands out pastry to reporters on the plane after a campaign event at Portsmouth International Airport, in Newington, N.H., Saturday, Nov. 3, 2012. (AP Photo/Charles Dharapak)

MENTOR, Ohio (AP) ? Reaching for the finish line, Republican Mitt Romney and President Barack Obama embarked Saturday on the final 72-hour haul of their long, grinding quest for victory, swatting at one another over what should motivate Americans to vote, which candidate they can trust and offering dueling pictures of what the next four years should bring.

Romney opened a three-state campaign day in New Hampshire by faulting Obama for telling supporters a day earlier that voting would be their "best revenge."

"Vote for 'revenge?'" the GOP candidate asked, oozing incredulity. "Let me tell you what I'd like to tell you: Vote for love of country. It is time we lead America to a better place."

The Republican nominee released a TV ad carrying the same message.

Obama, campaigning in the uber-battleground of Ohio, countered with a final reminder that Tuesday's election is "not just a choice between two candidates or two parties, it's a choice between two different visions for America." The president offered himself as the candidate voters can trust, renewing his criticism of Romney for what he said were misleading ads suggesting that automakers were shifting U.S. jobs to China.

The president urged voters in an overflow room to shepherd their friends, neighbors and girlfriends to the polls to vote early, tacking on this very practical caveat: "You should convince them to vote for me before you drag them off to the polls."

Campaign spokesman Jennifer Psaki said the president's revenge comment was nothing more than a reminder that if voters think Romney's policies are "a bad deal for the middle class, then you have power, you can go to the voting booth and cast your ballot."

Whatever their motivation, 27 million Americans already have cast ballots around the country.

On the last day of early voting in Florida, voters at some sites in Miami-Dade and Broward counties were waiting up to four hours to cast ballots. Sen. Bill Nelson, D-Fla., asked his state's Republican governor to extend early voting at least through Sunday, citing "an untold number of voters being turned away or becoming too discouraged to vote."

Before leaving Washington, Obama tended to presidential business as he led a briefing at the government's disaster relief agency on the federal response to Superstorm Sandy. He said the recovery effort still has a long way to go but pledged a "120 percent effort" by all those involved.

"There's nothing more important than us getting this right," Obama said, keenly aware that a spot-on government response to the storm also was important to his political prospects. Then he began his own three-state campaign day.

After holding mostly small and midsize rallies for much of the campaign, Obama's team is holding a series of larger events this weekend aimed at drawing big crowds in battleground states. Still, the campaign isn't expecting to draw the massive audiences Obama had in the closing days of the 2008 race, when his rallies drew more than 50,000.

Obama's closing weekend also includes two joint events with former President Bill Clinton: a rally Saturday night in Virginia and an event Sunday in New Hampshire. The two presidents had planned to campaign together across three states earlier this week, but that trip was called off because of Sandy. And, of course, there is always Ohio.

In a whiff of 2008 nostalgia, some of Obama's traveling companions from his campaign four years ago joined him on the road for the final days of his last campaign. Among them are Robert Gibbs, who served as Obama's first White House press secretary, and Reggie Love, Obama's former personal aide who left the White House earlier this year.

Likewise, virtually Romney's entire senior team left the campaign's Boston headquarters to travel with Romney for the contest's final three days. Their presence for the campaign's waning hours is an admission that the strategy and planning is largely complete. His schedule has been set, the ads have been placed and Romney's message has been decided.

The tight inner circle that has worked with him for several years in most cases plan to enjoy the final moments on the campaign trail as Romney's side.

"It's been a long road," Ann Romney told reporters aboard the campaign plane, offering breakfast pastries to Secret Service agents and reporters alike. After campaigning on her own for the past month, she joined her husband for the final swing.

Romney hosted a massive rally Friday night in West Chester, Ohio, drawing more than 10,000 people to the Cincinnati area for an event that featured rock stars, sports celebrities and dozens of Republican officials. It was a high-energy event on a cold night designed to kick off his own sprint to the finish.

After his Saturday morning rally on the New Hampshire seacoast, he had an afternoon appearance in Iowa and two more in Colorado. He shifted an original plan to campaign in Nevada on Sunday in favor of a schedule likely to bring him back to Iowa, Ohio, Pennsylvania and Virginia.

Obama's Saturday itinerary had him heading from Ohio to Milwaukee and Dubuque, Iowa, and ending the day in Bristow, Va. On Sunday, he was taking his campaign to New Hampshire, Florida, Colorado and, yes, Ohio.

GOP running mate Paul Ryan was in Ohio, too, and he took issue Saturday with Obama's "revenge" comment.

"We don't believe in revenge; we believe in change and hope," he said "We actually do."

"We're not just picking a president for the next four years," Ryan told voters. "We are literally picking the trajectory of this country ... for at least a generation."

Polling shows the race remains a tossup heading into the final days. But Romney still has the tougher path; he must win more of the nine most-contested states to reach 270 electoral votes: Ohio, Florida, Virginia, North Carolina, Colorado, Nevada, Wisconsin, Iowa and New Hampshire.

Romney has added Pennsylvania to the mix, hoping to end a streak of five presidential contests where the Democratic candidate prevailed in the state. Obama won Pennsylvania by more than 10 percentage points in 2008; the latest polls in the state give him a 4 to 5-point margin. Romney will campaign in the Philadelphia suburbs on Sunday. Obama aides scoff at the Romney incursion, but they are carefully adding television spending in the state and are sending Clinton to campaign there Monday.

According to one group that tracks television advertising, Romney, the Republican party and the groups supporting him are spending $11 million on television advertising in Pennsylvania in the campaign's final week. Obama's advertising in the state totals $3.7 million.

In crucial early voting, Obama holds an apparent lead over Romney in key states. But Obama's advantage isn't as big as the one he had over John McCain four years ago, giving Romney hope that he could make up that gap in Tuesday's election.

About 27 million people already have voted in 34 states and the District of Columbia. No votes will be counted until Election Day, but several battleground states are releasing the party affiliation of people who have voted early. So far, Democratic voters outnumber Republicans in Florida, Iowa, Nevada, North Carolina and Ohio. Republicans have the edge in Colorado.

___

Benac reported from Washington. Associated Press writers Julie Pace and Stephen Ohlemacher in Washington, Kasie Hunt and Steve Peoples in New Hampshire, Philip Elliott in Ohio and Suzette Laboy in Miami contributed to this report.

___

Follow Jim Kuhnhenn on Twitter: https://twitter.com/jkuhnhenn

Follow Nancy Benac on Twitter: http://www.twitter.com/nbenac

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-11-03-Presidential%20Campaign/id-42ebccd9caa2464ebce306c48764cadf

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New MS drug proves effective where others have failed

Friday, November 2, 2012

A drug which 'reboots' a person's immune system has been shown to be an effective treatment for multiple sclerosis (MS) patients who have already failed to respond to the first drug with which they were treated (a 'first-line' therapy), as well as affected individuals who were previously untreated. The results of these two phase III clinical trials were published today in the journal The Lancet.

The new studies, sponsored by Genzyme (a Sanofi company) and Bayer Schering Pharma, showed that alemtuzumab significantly reduces the number of attacks (or relapses) experienced by people with MS compared to interferon beta-1a (known commercially as Rebif). This was seen both in patients who had not previously received any treatment (drug-na?ve) and those who have continued to show disease activity whilst taking an existing treatment for MS.

In the CARE MSII trial, confined to patients who had recently relapsed on a licenced therapy, new episodes were reduced by 49 per cent more than that achieved by the current standard treatment for MS, interferon beta-1a. Over a two year period, 65 per cent of patients on alemtuzumab compared to 47 per cent of patients on interferon remained relapse free. Additionally, alemtuzumab reduced the risk of acquiring disability by 42 per cent compared to interferon: disability worsened in 20% of interferon patients and 13% of alemtuzumab patients. Moreover, at the end of the study, on average, patients taking alemtuzumab had less disability than when they started the trial whereas those on interferon had experienced worsening disability.

"Our research shows the transformative effect that alemtuzumab can have for people with MS. Patients who continue to show disease activity while on their initial therapy are especially difficult to treat. Now, we have shown that alemtuzumab works where first-line drugs have already failed. It not only reduces the chances of disability associated with MS but may even result in long-term clinical improvements," said Professor Alastair Compston from the University of Cambridge, principal investigator on both studies and Chair of the Steering Committee which oversaw these and earlier clinical trials.

For the study (CARE MS II), researchers recruited 840 MS patients (of whom 628 were used for the principal analysis) who had been treated previously but had recently relapsed during their therapy. They were divided in a ratio of 2:1 to receive either alemtuzumab or interferon beta-1a. Their disability was then assessed every three months for two years by a researcher who was not made aware of which drug the patient had received. Additionally, they had annual scans to assess the lesions and brain shrinkage caused by MS.

Alemtuzumab was found significantly to reduce the risk of having another relapse of MS or becoming disabled over the next two years, compared to one of the most effective licensed therapies for similar cases of MS, interferon beta-1a. Additionally, most patients on alemtuzumab experienced an improvement in disability, which was not seen after treatment with interferon-beta 1a. The brain scans showed that alemtuzumab not only reduced the number of new lesions, compared to interferon beta-1a, but also reduced the rate of brain shrinkage that occurs in MS as tissue is damaged.

"Although other MS drugs have emerged over the last year ? which is certainly good news for patients ? none has shown superior effects on disability when compared to interferon except alemtuzumab. Additionally, no other treatment has led to improvements in disability," said Dr Alasdair Coles, lead author of the paper and a clinician from the University of Cambridge.

MS is an autoimmune disease in which the body's immune system mistakenly attacks nerve fibres and their protective insulation, the myelin sheath, in the central nervous system. The resulting damage prevents the nerves from 'firing' properly and ultimately leads to the loss of the nerve fibre, resulting in physical and cognitive disabilities. The results of a second phase III clinical trial (CARE MS I) also examined the effectiveness of alemtuzumab against the drug interferon beta-1a but in 581 drug-na?ve patients.

It found that alemtuzumab reduced the number of attacks experienced by people with relapsing-remitting MS by 55 per cent over and above that achieved by interferon beta-1a. Over a two year period, 78 per cent of patients on alemtuzumab compared to 59 per cent of patients on interferon remained relapse free. The proportion of patients experiencing worsening of disability on this trial was slightly lower after alemtuzumab than interferon beta-1a, but this result was not statistically significant.

For both studies, the principal side-effect of treatment with alemtuzumab was the development of other autoimmune diseases. During the trials, roughly 20 per cent of patients developed thyroid autoimmunity and 1 per cent developed an immune thrombocytopenia. Previous work has shown that up to 30 per cent of patients may develop autoimmune thyroid disease over time.

Laboratory work of the Cambridge research team, led by Dr Coles, is investigating how to detect people who are susceptible to these side-effects (funded by the Freemasons' Grand Charity and the Multiple Sclerosis Society in the UK). Additionally, they are currently recruiting for a trial of alemtuzumab in combination with a novel drug to reduce the risk of autoimmune diseases developing as a side-effect of taking alemtuzumab, funded by the Moulton Charitable Foundation and the Medical Research Council (MRC). Both Professor Alastair Compston and Dr Alasdair Coles are supported by the NIHR Biomedical Research Centre, Cambridge.

"Although alemtuzumab causes potentially serious side-effects, these can be identified and treated provided a monitoring schedule is carefully followed. Additionally, we think that we can identify which patients are at risk of autoimmune disease after alemtuzumab, and we are currently recruiting for a clinical trial which will explore whether we can use a drug to reduce the risk of autoimmunity in those at highest risk," said Dr Coles.

This brings to conclusion a unique programme for the development of a drug for MS that began in Cambridge in 1991. Never before has an MS drug been tested in clinical outcomes against such a high hurdle, an active first-line drug, in both one phase II trial and two phase III trials; and no drug for MS has been shown to be more effective, in both reducing the risk of disability and reducing the rate of brain atrophy, when compared to another active treatment.

Decisions on drug licences for alemtuzumab (known commercially as Lemtrada) by the European and US regulatory authorities are expected in 2013.

MS affects almost 100,000 people in the UK, 400,000 in the United States and several million worldwide.

###

University of Cambridge: http://www.cam.ac.uk

Thanks to University of Cambridge for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/124986/New_MS_drug_proves_effective_where_others_have_failed

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Exxon adding to Gulf of Mexico position

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