Thursday, February 28, 2013

Elon Musk says Tesla will repay Department of Energy loan well before 2022 due date

Elon Musk says Tesla will repay Department of Energy loan well before deadline

Tesla's CEO, Elon Musk, has been the focus of many headlines lately due to a certain, well-documented kerfuffle with The New York Times. Today, however, the automotive company's chief isn't questioning any reviews. Instead, he's taken to the Advanced Research Projects Agency for Energy summit to share his belief that Tesla Motors will pay off that $465 million loan from the US Department of Energy well ahead of when it's expected to -- in five years, rather than ten, to be precise. Musk's comments shouldn't come as a surprise, however, given that the Model S maker has been paying its DOE-borrowed cash on time and before the deadlines -- something it's been able to accomplish despite being far from a money-making machine at the moment. For the Department of Energy, meanwhile, this all sounds like music to the ears, especially since it knows that not all EVs always work out as planned.

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Source: Technology Review

Source: http://www.engadget.com/2013/02/27/elon-musk-tesla-doe-loan/

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Human trials for Streptococcus A vaccine

Human trials for Streptococcus A vaccine [ Back to EurekAlert! ] Public release date: 28-Feb-2013
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Contact: Helen Wright
helen.wright@griffith.edu.au
07-373-54288
Griffith University

Griffith research hits critical phase

Griffith University's Institute for Glycomics has launched human trials for a vaccine against Streptococcus A, the germ that causes rheumatic fever.

Severe damage to a patient's heart is just one of the possible long term consequences of rheumatic fever. Former Prime Minister Kevin Rudd has twice had heart surgery to repair damage suffered from rheumatic fever when he was a child.

Professor Michael Good, Principal Research Leader at the Institute for Glycomics has devoted more than 20 years to beating this disease. The key to the vaccine lies in targeting a particular protein found on the surface of Strep A bacteria.

"Previous studies have shown that the vaccine induces a very effective immune response in rabbits and mice," Professor Good said.

"The next important step is to ensure that it is safe and does not cause any adverse effects in people, in particular that the vaccine itself doesn't cause any heart damage."

Professor James McCarthy, Head of the Infectious Diseases program at the Queensland Institute of Medical Research will carry out the year-long trial involving 20 healthy adults.

"Participants will be monitored very closely for the next 12 months," Professor McCarthy said.

"Each volunteer will be given two doses of the vaccine and we'll be watching carefully for any signs of heart problems."

Rheumatic fever is a major issue in remote Aboriginal and Torres Strait Islander communities in northern Australia.

"Infection rates in these remote Queensland communities are among the highest in the world. Nine out of every ten sufferers in this State are Aboriginal or Torres Strait Islander people," Professor Good said.

###

The vaccine trial is funded by the Co-operative Research Centre for Aboriginal and Torres Strait Islander Health.

Much of Professor Good's early work was backed by the National Heart Foundation, The Prince Charles Hospital Research Foundation, the United States National Institutes of Health, the Co-operative Research Centre for Vaccine Technology, the Perpetual Foundation and the NHMRC



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Human trials for Streptococcus A vaccine [ Back to EurekAlert! ] Public release date: 28-Feb-2013
[ | E-mail | Share Share ]

Contact: Helen Wright
helen.wright@griffith.edu.au
07-373-54288
Griffith University

Griffith research hits critical phase

Griffith University's Institute for Glycomics has launched human trials for a vaccine against Streptococcus A, the germ that causes rheumatic fever.

Severe damage to a patient's heart is just one of the possible long term consequences of rheumatic fever. Former Prime Minister Kevin Rudd has twice had heart surgery to repair damage suffered from rheumatic fever when he was a child.

Professor Michael Good, Principal Research Leader at the Institute for Glycomics has devoted more than 20 years to beating this disease. The key to the vaccine lies in targeting a particular protein found on the surface of Strep A bacteria.

"Previous studies have shown that the vaccine induces a very effective immune response in rabbits and mice," Professor Good said.

"The next important step is to ensure that it is safe and does not cause any adverse effects in people, in particular that the vaccine itself doesn't cause any heart damage."

Professor James McCarthy, Head of the Infectious Diseases program at the Queensland Institute of Medical Research will carry out the year-long trial involving 20 healthy adults.

"Participants will be monitored very closely for the next 12 months," Professor McCarthy said.

"Each volunteer will be given two doses of the vaccine and we'll be watching carefully for any signs of heart problems."

Rheumatic fever is a major issue in remote Aboriginal and Torres Strait Islander communities in northern Australia.

"Infection rates in these remote Queensland communities are among the highest in the world. Nine out of every ten sufferers in this State are Aboriginal or Torres Strait Islander people," Professor Good said.

###

The vaccine trial is funded by the Co-operative Research Centre for Aboriginal and Torres Strait Islander Health.

Much of Professor Good's early work was backed by the National Heart Foundation, The Prince Charles Hospital Research Foundation, the United States National Institutes of Health, the Co-operative Research Centre for Vaccine Technology, the Perpetual Foundation and the NHMRC



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-02/gu-htf022813.php

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Gonorrhoea cases soar 25 percent in England as superbugs take hold

LONDON (Reuters) - Gonorrhoea cases have soared by 25 percent in the past year in England as superbug or drug-resistant strains of the sexually transmitted infection (STI) take hold worldwide, British health officials said on Wednesday.

Nearly 21,000 new cases had been diagnosed in 2011, with more than a third of cases in gay men and more than a third in people who have had gonorrhoea before, the UK Health Protection Agency (HPA) said in a statement.

Effective treatment with antibiotics has been compromised by growing resistance, it said, noting "a drift towards decreased susceptibility" of gonorrhoea infections to drugs called cephalosporins which are normally recommended as treatment.

"We are seriously concerned about continuing high levels of gonorrhoea transmission and repeat infection," said Gwenda Hughes, the HPA's head of STI surveillance.

A strain of gonorrhoea that was resistant to all recommended antibiotics was found in Japan in 2008, scientists said in 2011. They warned then it could transform a once easily treatable infection into a global health threat.

Last year the World Health Organisation said cases of drug-resistant gonorrhoea had spread across the world.

Gonorrhoea is a bacterial STI which, if left untreated, can lead to pelvic inflammatory disease, ectopic pregnancy, stillbirths and infertility in both men and women.

It is one of the most common sexually transmitted diseases in the world and is most prevalent in south and southeast Asia and sub-Saharan Africa. In the United States alone, according to the Centers for Disease Control and Prevention, the number of cases is estimated at about 700,000 a year.

The emergence of superbugs has been driven by the overuse and misuse of antibiotics, which help fuel genetic mutations within the bacteria.

(Reporting by Kate Kelland; Editing by Louise Ireland)

Source: http://news.yahoo.com/gonorrhoea-cases-soar-25-percent-england-superbugs-hold-134347867.html

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Wednesday, February 27, 2013

Health Club San Mateo Boot Camp 2/26/13: 6 Pack Abs? | Brien Shamp

Health Club San Mateo Boot Camp 2/26/13: 6 Pack Abs?

3 Phase Warm-Up:

Phase 1: ?Foundation Mobility Training (5 Min) *Review WOD here and after cardio as needed. Assign groups here also.

Phase 2: None

Phase 3:?Cardio: Jog/Walk: 3 min

*Set Gym Boss or Interval App to: 40s work time, 15s rest, 6 sets


CORE: Perform 3 Rounds for 40s in a circuit (rest 15 s in between)

1.??? MB Kneeling Side Bend *Place ball on head- lift ball to make harder *Lock Shoulders back & down *Squeeze shoulder blades *Keep 3B?s

2.??? SB/Plate Kneeling Reverse Wood Chops with Pivot (20s each side) *Lock shoulders back & down

3.??? MB Sit Up Partner Toss *Wide feet *Dig heels *Both partners do this at the same time

4.??? Alternating Reverse Hyperextension *Alt one leg at a time

5.??? Lower Ab Curl * Pull Up Hang *3B?s *Move from core

6.??? Walking Side Step with Band-Straight Legs (20s each direction) *3B?s

7.??? Glider Roll-Out *Move from hip *3B?s

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*After all 7 exercises are complete perform the following ladder exercises?(Relax Heels):

?

Round 1:

In-In-Out-Out (Fwd)-2 leading with each foot

In-In-Out-Out (Fwd-Skip One)-2 leading with each foot

In-In-Out-Out (Back)- 2 leading with each foot

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Round 2:

Wide Skip-2 leading with each foot

Hop Scotch-2

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Round 3:

Hop Scotch with 1 Foot In-2 leading with each foot

Run Through for Speed-2 leading with each foot

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Circle Time: Cool down & stretch (5 minutes)

If you can?t see the video above go to:?Boot Camp BLOG

Please add your comments below on the workout.

Try Health Club San Mateo Boot Camp for Only $29 for 3 Sessions:?www.ShampsBootCamps.com

Your friend & coach,

Brien

**************************************************************************

Join me on?Facebook (click here)?for answers to all your health, fitness, and nutrition questions.

Please Write Me a Review on Yelp:?Belmont Boot Camp,?Burlingame Boot Camp,?Redwood City Boot Camp,?Personal Training & Nutrition

**************************************************************************

I work with those who desire weight & fat loss, pain reduction and stress management through comprehensive exercise, nutrition & lifestyle strategies. My dream? is to coach those who seek my help live their passions with happiness & love.

Thank you for allowing me to help you.

**************************************************************************

Check our life-changing fitness and nutrition programs to help you live your healthiest, fittest, and most energetic life ever!

Brien Shamp BS CSCS CMT CHEK NLC II

Personal Trainer, Nutrition and Lifestyle Coach

www.BrienShamp.com
www.Shamp?sBootCamps.com
www.10 DayDetox.com
www.21DayDetox.com

650-654-4604

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Source: http://www.brienshamp.com/2013/02/26/health-club-san-mateo-boot-camp-22613-6-pack-abs%E2%80%8F/

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Defense secretary nominee Hagel faces big step to confirmation

In this Jan. 31, 2013 file photo, former Nebraska Sen. Chuck Hagel testifies at his Senate Armed Services Committee??Barring some unforeseen bombshell, Chuck Hagel will most likely win Senate confirmation as defense secretary by the end of this week.

The Republican former senator from Nebraska looks on track to clear the biggest hurdle on Tuesday: A vote to end debate on his contentious nomination and move to a final up-or-down ballot -- the outcome of which is not seriously in doubt.

What was unclear as of late Monday was whether Hagel's Republican opponents would use up all or just some of the 30 hours of debate they will have under Senate rules between the two votes. Aides on both sides predicted that Hagel's critics would want to cycle through some of their complaints -- that he cannot be trusted to manage the U.S.-Israel security relationship, or confront Iran over its nuclear program -- but would not foretell precisely when the final vote would occur. Democratic aides hoped for Tuesday, accepted Wednesday, and groused about the possibility of Thursday.

It was not clear how the sustained battering would affect Hagel's tenure at the Pentagon. But the rough handling he got from his fellow Republicans and former colleagues shows one thing for sure: The former lawmaker cannot count on getting the benefit of the doubt from Congress as he moves to deal with spending cuts that start coming into force on Friday, or takes on challenges overseas like the withdrawal from Afghanistan. (Top House Republicans don't get a vote, but some came out against Hagel, presaging combative exchanges when he goes before the House Armed Services Committee).

But first, the confirmation process.

Democrats have set up a cloture vote ? a vote to end debate on the Republican former senator?s nomination ? for midday on Tuesday. A similar effort fell short in the face of an unprecedented GOP filibuster two weeks ago, with Democrats just one vote shy of the 60 needed to proceed to confirm Hagel. (The tally showed 58 votes in favor, but Democratic Senate Majority Leader Harry Reid changed his vote to ?no? in order to secure the right under parliamentary rules to bring up today?s vote).

Since then, however, Republican Senator Richard Shelby of Alabama has come out in favor of Hagel, and some of his colleagues have indicated they will back cloture unless some bombshell new allegation surfaces. The White House, meanwhile, flatly rejected a Republican call late last week to withdraw the nomination.

So the Senate is likely to all-but-certain to invoke cloture. But, under Senate rules, that starts the clock on a 30-hour debate before the final confirmation vote. Republicans could decide not to use the full 30 hours, but as of late Monday it was unclear whether they would do so. And even one objection would mean lawmakers would have to use up the full 30 hours ? putting off the last vote in Hagel?s rocky nomination process to late Wednesday or even early Thursday.

Democrats can count on 55 votes ? four more than the 51 needed to confirm Hagel. So the cloture vote is really the last real stab at derailing a nomination that drew fierce Republican opposition and generally tepid Democratic support and that briefly looked lost in the weeds after Hagel put in a decidedly poor performance in front of the Senate Armed Services Committee.

Source: http://news.yahoo.com/blogs/ticket/defense-secretary-nominee-hagel-faces-big-step-confirmation-114702931--politics.html

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Intel lands Altera as its biggest chip manufacturing customer to date

Intel lands Altera as its biggest chip manufacturing customer to date

Many of us see Intel as self-serving with its chip manufacturing, but that's not entirely true: it just hasn't had very large customers. A just-unveiled deal with Altera might help shatter those preconceptions. Intel has agreed to make some of the embedded technology giant's future field-programmable gate arrays (FPGAs) using a 14-nanometer process, giving Intel a top-flight customer while gets Altera a leg up over any rivals stuck on less efficient technologies. The pact may be just the start -- Intel VP Sunit Rikhi portrays the deal for Reuters as a stepping stone toward a greater role in contract chip assembly. We're not expecting Intel to snatch some business directly from the likes of GlobalFoundries and TSMC when many of their clients are ARM supporters, or otherwise direct competitors. However, we'll have to reject notions that Intel can't share its wisdom (and factories) with others.

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Via: Reuters

Source: Altera

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/4o5L_KJFMI4/

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Video: Man rescues dog from block of floating ice

Pifas, a three-year-old golden retriever mix, was rescued by a kind stranger who helped guide the dog to safety after it became stranded on a block of ice in a frozen lake.

NBCNews.com reports that Pifas disappeared from his owner?s home and was missing for over a week before he was spotted some 200 feet from shore on Lake Michigan by local resident Dave Kehnast.

?I was up on the fire escape there on the seventh floor and I saw him way out there, and so I grabbed the kayak and went out there,? Kehnast said.

When Kehnast realized the dog was not able to get back to shore on his own, he donned a wetsuit, got into a kayak and headed out to save the starving and confused dog, according to Opposing View.

Pifas? owner, Nerijus Steponavicius, said the dog had gotten out while his landlord was changing locks on the doors to his apartment building while Steponavicius was at school for the day.

Kehnast says Pifas was too afraid and confused to be picked up. Instead, Kehnast had to yell commands and encouragement to the dog to help guide him back to shore.

?I just kept encouraging him, ?here boy, here boy, here boy,?? Kehnast told Opposing Views. ?I got really close to him and he wanted to bite me so I just stayed on me and at that point I could get into the water and just hustled him along. I wanted to just grab him because it was shallow enough where I could stand, and I just wanted to get my hands on him but he wanted to bite me, it looked like. He didn?t want anyone touching him.?

The Chicago Fire Department also assisted, flying in a helicopter to help drive Pifas closer to shore.

After Pifas made it back to shore, he was taken to a nearby veterinary clinic for recovery and monitoring. He was reunited with Steponavicius, who reportedly learned of his dog?s rescue after family members alerted him to stories appearing on the news.

"He's really shy and he started jumping," Steponavicius said.

Of course, it was not an entirely happy ending for the adventurous golden retriever. Officials said Pifas had to be neutered before they agreed to turn him back over to his owner.

Source: http://news.yahoo.com/blogs/sideshow/man-rescues-dog-block-floating-ice-video-231555617.html

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MetroPCS shareholders to vote on T-Mobile merger March 28

T-Mobile SIM

Shareholders of MetroPCS are planning to hold a vote on March 28th to approve its previously-announced reverse merger with T-Mobile USA. The deal has been in the works for several months, and is technically a "reverse merger" because MetroPCS will be buying T-Mobile, even though it is the smaller company. Deutsche Telekom currently owns T-Mobile USA, and will have a 74-percent stake in the new company if the merger is approved. But because MetroPCS is a publicly held company, the shareholders must vote to approve the deal before it can go any further

Two different hedge funds -- P. Schoenfeld and Paulson & Co. -- which hold 2.3-percent and 8.7-percent of MetroPCS shares respectively, have expressed that they will vote against the merger. These funds believe MetroPCS shareholders aren't getting enough from the deal, which at this point is about $4.09 per share (or $1.5 billion in cash) and the remaining 26-percent of the newly merged company.

While the funds continue to urge other shareholders to consider voting against the deal, the MetroPCS board of directors is supporting the deal, as is Deutsche Telekom. The terms could certainly change before this becomes final, but at this point it looks as though MetroPCS and T-Mobile will indeed merge in the coming months, combining the 4th and 5th largest carriers in the U.S.

Source: MarketWatch



Source: http://feedproxy.google.com/~r/androidcentral/~3/-a2EgYc2mYA/story01.htm

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BGG Playlist: Date Night At Mohawk Bend, A New Speakeasy, And Sarah Silverman (Live!) |?Broke Girls Guide

www.brokegirlsguide.com:

Whew. We made it through awards season, which means we no longer have to hear endless chatter about who is going to what party and blah, blah, blah. It was all very fun, but now it's time to move on with our lives... Don't you think?

OK, fine, you're still gossiping about so-and-so's dress and how x, y, and z of your instagram friends managed to sneak into Seth MacFarlane's after party last night. And you are probably also still nursing a hangover from the Oscars drinking game we encouraged you to play. (Don't worry: Help is on the way). With all of this in mind, we've kept your Monday mellow and filled the week with good food and lots of laughs so as to ease you back into regular life as painlessly as possible.

Read the whole story at www.brokegirlsguide.com

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Source: http://www.huffingtonpost.com/2013/02/25/bgg-playlist-date-night-a_n_2762307.html

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CBA Wealthpackage Review ? Tomorrow Finance Blog

CBA has been a trusted financial institution in Australia?s banking industry since 1912. CBA?s unique advantage in the banking industry, allows them the opportunity to monitor borrowers? banking habits, so they can offer products that coincide with borrowers? needs.

?

CBA Offers Simplicity For Their Customers

CBA recognised that borrowers with many CBA products, deserve rewards, too. CBA?s answer to banking simplicity, resulted in the development of the Wealth package.

?

The Wealth package allows customers with multiple CBA banking products to reap the rewards of trusting CBA with their financial life. Borrowers with a minimum loan of $150,000 may be eligible for unlimited access to their transactional accounts without withdrawal or monthly fees. Wealth package customers with one Commonwealth Bank MasterCard Credit Card will be alleviated from annual credit card fees and additional cardholders fees that are typically charged.

?

Benefits and Savings

Commonwealth Bank Wealth package borrowers only pay an annual fee of $375 to receive the rewards, benefits and discounts offered by the Wealthpackage home loan. Borrowers will notice a savings right away if they are approved. Up-front Establishment Fees and Loan Service Fees are waived. Wealthpackage home loan customers will also notice an immediate savings in their interest rate with competitive 0.50% p.a. to 0.70% p.a. discounts off standard and variable interest rates, and line of credit home loans.

?

In addition to home loan savings, CBA offers benefits for personal loans that are held by Wealthpackage customers. Borrowers will receive a 0.50% p.a. discount off standard variable and fixed rate personal loans with a balance of at least $10,000. Borrowers are also relieved of the Establishment Fee.

?

CBA?s Wealthpackage benefits extend far beyond their financial accounts. Borrowers will be eligible for savings on their insurance products, too. CBA and CommInsure have teamed up to offer 10% discounts off home and contents insurance, 5% off investment home insurance, and 10% off car insurance premiums. Borrowers who apply for Total Care, Income Care and Income Care Plus Plans with a CBA Planning Adviser, automatically receive a 5% savings off their first year?s premium

Source: http://www.tomorrowfinance.com.au/blog/cba-wealthpackage-review/

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World's postal services struggle with lower demand

In this photo taken Friday, Feb. 15, 2013, postman John Lahmert delivers mail in rural Otaki, New Zealand. New Zealand is considering cutting letter deliveries from six days a week to three as global demand for postal services dwindles. (AP Photo/Nick Perry)

In this photo taken Friday, Feb. 15, 2013, postman John Lahmert delivers mail in rural Otaki, New Zealand. New Zealand is considering cutting letter deliveries from six days a week to three as global demand for postal services dwindles. (AP Photo/Nick Perry)

In this photo taken Friday, Feb. 15. 2013, postman John Lahmert loads his truck with mail in Otaki, New Zealand. New Zealand is considering cutting letter deliveries from six days a week to three as global demand for postal services dwindles. (AP Photo/Nick Perry)

In this photo taken Friday, Feb. 15, 2013, Sandra Vidulich is thrilled about her new leather boots delivered by postman John Lahmert in rural Otaki, New Zealand. New Zealand is considering cutting letter deliveries from six days a week to three as global demand for postal services dwindles. (AP Photo/Nick Perry)

In this photo taken on Friday, Feb. 15, 2013, semi-retired farmer Barry Georgeson collects his mail from postman John Lahmert in rural Otaki, New Zealand. New Zealand is considering cutting letter deliveries from six days a week to three as global demand for postal services dwindles. (AP Photo/Nick Perry)

In this photo taken Friday, Feb. 15, 2013, postman John Lahmert greets a customer from his delivery truck, in rural Otaki, New Zealand. New Zealand is considering cutting letter deliveries from six days a week to three as global demand for postal services dwindles. (AP Photo/Nick Perry)

(AP) ? Sandra Vidulich is so excited about the leather boots she ordered through Amazon that she rips open the box in front of the postman and tries them on.

"I looove them," she declares, as the driveway at her tree-lined home in rural New Zealand briefly becomes a catwalk. "They're cool."

For now, a boom in Internet shopping is helping keep alive moribund postal services across the developed world. But the core of their business ? letters ? is declining precipitously, and data from many countries indicate that parcels alone won't be enough to save them. The once-proud postal services that helped build modern society are scaling back operations, risking further declines.

The United Kingdom is preparing to wash its hands of mail deliveries entirely by selling the Royal Mail, which traces its roots back nearly 500 years to the reign of King Henry VIII.

The U.S. Postal Service sparked uproar this month when it announced plans to stop delivering letters on Saturdays. New Zealand is considering more drastic cuts: three days of deliveries per week instead of six.

It's only in the past few years that postal services have truly felt the pinch of the Internet. Revenues at the USPS, which delivers about 40 percent of the world's mail, peaked in 2007 at $75 billion.

But the decline since then has been rapid. USPS revenue in 2012 fell to $65 billion, and its losses were $15.9 billion. It handled 160 billion pieces of mail that year, down from 212 billion in 2007. And it had slashed its workforce by 156,000, or 23 percent.

Elsewhere, the news is just as grim. La Poste in France estimates that by 2015, it will be delivering 30 percent fewer letters than it did in 2008. Japan last year delivered 13 percent fewer letters than it did four years earlier. In Denmark, the postal service said letter volumes dropped 12 percent in a single year.

The Universal Postal Union, which reports to the United Nations, estimates that letter volumes worldwide dropped by nearly 4 percent in 2011 and at an even faster clip in developed nations. Developed countries closed 5 percent of their post offices in 2011 alone.

And while Internet shopping continues to grow, postal services that once profited from their monopoly on letters find themselves competing for parcels against private companies like FedEx.

U.S. Postmaster General Patrick Donahoe, in an interview with The Associated Press, said he doesn't believe the service can ever regain the revenue from packages it has lost from letters. He said axing Saturday mail deliveries, while keeping six-day-a-week package deliveries, will save the service about $2 billion a year.

Donahoe said he thinks ending Saturday letter deliveries will keep the USPS a solid proposition for years to come.

"People still go to their mailbox every day and they wait for their mail to come," he said. "It's part of American life."

And it has been since the beginning. The postal service's role was defined in the Constitution, and Benjamin Franklin was the first postmaster general. The short-lived Pony Express achieved an enduring place in American folklore. Even the modern system of highways and airline travel grew from pioneering routes developed by the postal service.

"It's easy to forget how central this institution was to commerce, public life, social affairs," said Richard John, a Columbia University professor who has written a book on the postal service. "It was once very, very important. Of course, that was then and this is now."

Even now, however, much depends on the post office. According to the Envelope Manufacturers Association, the postal service is at the core of a trillion-dollar mailing industry in the U.S. that employs more than 8 million people.

And for delivering a paper letter cheaply, there is simply no alternative. If rural residents were ever charged the actual cost of mail rather than the subsidized standard rate, John said, the costs would be prohibitive.

The value of the mail goes beyond money in many places, including rural New Zealand. The postal carrier serves as a focal point for the community.

John Lahmert, the postman who delivered the boots, has been delivering mail to farms around the North Island town of Otaki for 18 years. The 72-year-old independent contractor seems to know everybody on his route and doesn't mind stopping for a chat.

Noeline Saunders greets him at the gate, wondering if her citrus trees have arrived. Not yet, Lahmert tells her. Barry Georgeson, a semi-retired farmer, calls out a greeting and wanders down to pick up his letters.

"We don't like change," Georgeson said when asked about the possibility of mail coming just three times a week. But he said he could learn to live with it.

Many seemed resigned to a reduced service.

"I think people can genuinely understand that the world is changing," said New Zealand Prime Minister John Key. "And while some people are still very reliant on the mail, for a lot of people that's a fraction of the way they receive information."

About 7 in 10 Americans said they'd favor axing Saturday deliveries if it allowed the post office to deal with billions of dollars in debt, according to a poll by The New York Times and CBS News.

Some countries, including Australia, Canada and Sweden, have already cut deliveries to five days a week. Others are tinkering with partial privatizations.

Exactly what Britons might expect under a privatized service remains unclear. Some speculate it could mean cutbacks.

Royal Mail's Chief Executive Moya Greene declined to comment for this story: "We're simply not doing interviews about the planned sale," spokesman Mish Tullar wrote in an email.

In policy documents, the UK government said six-day-a-week deliveries and standardized letter prices remain vital but that private investors will provide more financial stability than "unpredictable" taxpayer funding.

While letter volumes are falling in developed nations, the reverse is true in some developing countries. In China, mail deliveries are up 56 percent since 2007, driven by a more than fourfold increase in premium express mail, according to figures from China Post.

Yet people in China are accustomed to having their mail show up late or disappear altogether. As Internet use increases in the developing world, mail may never become as essential as it has been elsewhere.

Not everybody is ready to give up on letters. Reader's Digest sends out about 500,000 pieces of mail each week to people in Australia, New Zealand, Singapore and Malaysia as it tries to entice them to buy its merchandise.

"A lot of players are going for a digital strategy, and fewer are doing the direct-mail approach," said Walter Beyleveldt, managing director for the Asia Pacific region. "Because of that, the mailbox will get emptier. It will potentially become an exciting place to go and look."

New Zealanders, however, may be looking there half as often as early as next year, if proposed changes to the New Zealand Post's charter are approved.

The government is accepting public comments until mid-March. A quarter of those received so far were mailed in, a rate considered unusually high.

The other 75 percent? Email.

___

Joe McDonald in Beijing, Yuri Kageyama in Tokyo, Lori Hinnant in Paris, Cassandra Vinograd in London, Pauline Jelinek in Washington and Jan Olsen in Copenhagen, Denmark, contributed to this report. AP researchers Yu Bing and Monika Mathur also contributed.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-02-26-Dwindling%20Deliveries/id-29c79bebac954eaeb9372dcbc24c3ada

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Tuesday, February 26, 2013

Last Call: Disrupt NY Startup Battlefield Apps Are Due Tonight

disrupt-1This is it! Today, Monday, February 25, is the very last day to submit applications to Disrupt NY's Startup Battlefield. They have to be submitted and completed by 11:59 PST tonight. Stop procrastinating and get those apps in.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/wJT830RpeGE/

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Samsung confirms Galaxy S IV will debut on March 14th

It began as a seemingly awkward Jack Nicholson introduction of the very long list on nominees, but the Best Picture denouement?at a very long Oscars ceremony on Sunday turned into a surprise appearance by Michelle Obama, via satellite from the Governors' Ball in Washington, D.C.?where earlier she had sat next to Chris Christie?to introduce and announce the winner,?Argo.?

Source: http://news.yahoo.com/samsung-confirms-galaxy-iv-debut-march-14th-140042002.html

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Cricket-South Africa vs Pakistan - third test scoreboard

Sun Feb 24, 2013 3:21pm GMT

PRETORIA, Feb 24 (Reuters) - Scoreboard at the end of the third test, on day three, between South Africa and Pakistan at Centurion on Sunday.          South Africa won by an innings and 18 runs to clinch the three-match series 3-0.         South Africa first innings 409 (AB de Villiers 121, H. Amla 92, V. Philander 74; Rahat Ali 6-127)     Pakistan first innings 156 (Younus Khan 33; K. Abbott 7-29)     Pakistan second innings (following on, 14-1 overnight)   Mohammad Hafeez b Steyn                   0  Azhar Ali run out                        27  Younus Khan c Smith b Steyn              11  Imran Farhat c De Villiers b Abbott      43   Misbah-ul-Haq c De Villiers b Kleinveldt  5  Asad Shafiq c Philander b Kleinveldt      6  Sarfraz Ahmed c Elgar b Steyn            40  Saeed Ajmal lbw b Steyn                  31  Ehsan Adil c Kleinveldt b Abbott         12  Rahat Ali lbw b Peterson                 22  Mohammad Irfan not out                    6  Extras (b-9, lb-10, nb-2, w-11)          32       Total (all out, 78 overs)            235     Fall of wickets: 1-0 2-39 3-93 4-107 5-107 6-114 7-183 8-202 9-202 10-235     Bowling: D. Steyn 23-5-80-4, V. Philander 15-4-32-0 (w2), K. Abbott 17-7-39-2 (nb2), R. Kleinveldt 13-2-33-2 (w1), R. Peterson 10-2-32-1          South Africa won the toss and elected to bat.       (Compiled by Nick Said; editing by Tom Pilcher; nick.said@thomsonreuters.com +27832722948 Messaging nick.said.thomsonreuters.com@reuters.net)

Source: http://feeds.reuters.com/~r/reuters/UKCricketNews/~3/gY0VyJSb-Gk/cricket-pakistan-scoreboard-idUKL4N0BO0AL20130224

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Monday, February 25, 2013

Small molecules in the blood might gauge radiation effects after exposure

Small molecules in the blood might gauge radiation effects after exposure [ Back to EurekAlert! ] Public release date: 25-Feb-2013
[ | E-mail | Share Share ]

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Medical Center

  • Currently, doctors have no way to accurately measure damage to the body soon after a person is exposed to ionizing radiation.
  • It is therefore difficult to know whether a person is likely to suffer serious effects after an occupational or accidental exposure.
  • This animal study shows that radiation exposure alters the levels of certain small molecules in the blood, perhaps offering a reliable measure of damage to the body.

COLUMBUS, Ohio Ohio State University cancer researchers have identified molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation.

The animal study, led by researchers at The Ohio State Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC James), shows that X-rays or gamma rays alter the levels of certain molecules called microRNA in the blood in a predictable way.

If verified in human subjects, the findings could lead to new methods for rapidly identifying people at risk for acute radiation syndrome after occupational exposures or accidents such as the recent Fukushima Daiichi nuclear reactor incident. The microRNA markers might also help doctors plan radiation therapy for individual patients by taking into account how different people respond to radiation treatment, the researchers say.

The findings are reported in the journal PLOS ONE.

"Our paper reports the identification of a panel of microRNA markers in mice whose serum levels provide an estimate of radiation response and of the dose received after an exposure has occurred," says senior author Dr. Arab Chakravarti, chair and professor of Radiation Oncology, the Max Morehouse Chair in Cancer Research and co-director of the Brain Tumor Program.

"Accurate dose evaluation is critical for making medical decisions and for the timely administration of therapy to prevent or reduce acute and late effects."

The findings might also one day allow doctors to evaluate radiation toxicity during the course of therapy based on an individual's biology. "This would particularly benefit leukemia and lymphoma patients who receive total body irradiation in preparation for stem-cell transplantation," Chakravarti says.

First author Dr. Naduparambil Jacob, a research assistant professor in radiation oncology, noted that the study could be an important step in the development of biological dosimetry, or biodosimetry, a technology for identifying people at risk for acute radiation illnesses that develop within weeks of radiation exposure, and cancers and degenerative diseases that can occur months or years later.

"Biodosimetry is an emerging concept that could enable us to identify individuals who need immediate treatment after a radiation exposure and to better develop personalized radiation treatment plans for patients," Jacob says.

For this study, Chakravarti, Jacob and their colleagues evaluated dose-dependent changes in levels of 88 individual microRNAs in serum from mice after a single acute radiation exposure, and after fractionated doses of radiation that are typical of radiation treatment prior to stem-cell transplantation. Samples were collected from exposed and control animals 24 or 48 hours after exposure.

Key technical findings include:

  • After a one-time exposure, miRNA-150 showed a clear decrease over time with increasing radiation dose, with a drop of 30 percent after 24 hours and of 50 percent after 48 hours, even at the lowest exposure of one gray of radiation.
  • miRNA-200b and miRNA-762 showed increased levels after radiation exposure, with the changes more pronounced in animals receiving higher doses.
  • Animals receiving fractioned doses showed similar changes; e.g., miRNA-150 dropped about 50 percent after 24 hours in animals receiving 4 gray.

###

Funding from the NIH/National Cancer Institute (grant CA148190, CA108633) and a Brain Tumor Funders Collaborative Grant supported this research.

Other researchers involved in this study were James V. Cooley, Tamara N. Yee, Jidhin Jacob and Hansjuerg Alder, The Ohio State University; Priyankara Wickramasinghe, The Wistar Institute; and Kirsteen H. Maclean, NanoString Technologies.

The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute strives to create a cancer-free world by integrating scientific research with excellence in education and patient-centered care, a strategy that leads to better methods of prevention, detection and treatment. Ohio State is one of only 41 National Cancer Institute (NCI)-designated Comprehensive Cancer Centers and one of only seven centers funded by the NCI to conduct both phase I and phase II clinical trials. The NCI recently rated Ohio State's cancer program as "exceptional," the highest rating given by NCI survey teams. As the cancer program's 210-bed adult patient-care component, The James is a "Top Hospital" as named by the Leapfrog Group and one of the top cancer hospitals in the nation as ranked by U.S.News & World Report.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Small molecules in the blood might gauge radiation effects after exposure [ Back to EurekAlert! ] Public release date: 25-Feb-2013
[ | E-mail | Share Share ]

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Medical Center

  • Currently, doctors have no way to accurately measure damage to the body soon after a person is exposed to ionizing radiation.
  • It is therefore difficult to know whether a person is likely to suffer serious effects after an occupational or accidental exposure.
  • This animal study shows that radiation exposure alters the levels of certain small molecules in the blood, perhaps offering a reliable measure of damage to the body.

COLUMBUS, Ohio Ohio State University cancer researchers have identified molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation.

The animal study, led by researchers at The Ohio State Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC James), shows that X-rays or gamma rays alter the levels of certain molecules called microRNA in the blood in a predictable way.

If verified in human subjects, the findings could lead to new methods for rapidly identifying people at risk for acute radiation syndrome after occupational exposures or accidents such as the recent Fukushima Daiichi nuclear reactor incident. The microRNA markers might also help doctors plan radiation therapy for individual patients by taking into account how different people respond to radiation treatment, the researchers say.

The findings are reported in the journal PLOS ONE.

"Our paper reports the identification of a panel of microRNA markers in mice whose serum levels provide an estimate of radiation response and of the dose received after an exposure has occurred," says senior author Dr. Arab Chakravarti, chair and professor of Radiation Oncology, the Max Morehouse Chair in Cancer Research and co-director of the Brain Tumor Program.

"Accurate dose evaluation is critical for making medical decisions and for the timely administration of therapy to prevent or reduce acute and late effects."

The findings might also one day allow doctors to evaluate radiation toxicity during the course of therapy based on an individual's biology. "This would particularly benefit leukemia and lymphoma patients who receive total body irradiation in preparation for stem-cell transplantation," Chakravarti says.

First author Dr. Naduparambil Jacob, a research assistant professor in radiation oncology, noted that the study could be an important step in the development of biological dosimetry, or biodosimetry, a technology for identifying people at risk for acute radiation illnesses that develop within weeks of radiation exposure, and cancers and degenerative diseases that can occur months or years later.

"Biodosimetry is an emerging concept that could enable us to identify individuals who need immediate treatment after a radiation exposure and to better develop personalized radiation treatment plans for patients," Jacob says.

For this study, Chakravarti, Jacob and their colleagues evaluated dose-dependent changes in levels of 88 individual microRNAs in serum from mice after a single acute radiation exposure, and after fractionated doses of radiation that are typical of radiation treatment prior to stem-cell transplantation. Samples were collected from exposed and control animals 24 or 48 hours after exposure.

Key technical findings include:

  • After a one-time exposure, miRNA-150 showed a clear decrease over time with increasing radiation dose, with a drop of 30 percent after 24 hours and of 50 percent after 48 hours, even at the lowest exposure of one gray of radiation.
  • miRNA-200b and miRNA-762 showed increased levels after radiation exposure, with the changes more pronounced in animals receiving higher doses.
  • Animals receiving fractioned doses showed similar changes; e.g., miRNA-150 dropped about 50 percent after 24 hours in animals receiving 4 gray.

###

Funding from the NIH/National Cancer Institute (grant CA148190, CA108633) and a Brain Tumor Funders Collaborative Grant supported this research.

Other researchers involved in this study were James V. Cooley, Tamara N. Yee, Jidhin Jacob and Hansjuerg Alder, The Ohio State University; Priyankara Wickramasinghe, The Wistar Institute; and Kirsteen H. Maclean, NanoString Technologies.

The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute strives to create a cancer-free world by integrating scientific research with excellence in education and patient-centered care, a strategy that leads to better methods of prevention, detection and treatment. Ohio State is one of only 41 National Cancer Institute (NCI)-designated Comprehensive Cancer Centers and one of only seven centers funded by the NCI to conduct both phase I and phase II clinical trials. The NCI recently rated Ohio State's cancer program as "exceptional," the highest rating given by NCI survey teams. As the cancer program's 210-bed adult patient-care component, The James is a "Top Hospital" as named by the Leapfrog Group and one of the top cancer hospitals in the nation as ranked by U.S.News & World Report.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-02/osum-smi022113.php

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Love & Relationship | Barely Supermommy

Hi all!!

I?ve changed my blog?s theme. Big or not?? Easy to read, right?? ;)

Anyway, this time I?m reposting this write-up I found on a FB page. It?s about relationship. Since I?m only married for 2 years plus, nothing much I can write on my own. Even if I wrote it, you wouldn?t believe me.. I know!! Haha..

This article is from an FB page Beautiful [Me]

Beautifully written to remind us about appreciating our partner. Love is more than a feeling, it?s a decision. I have many youngsters writing to me about wanting to get married and build a family after reading my blog!!?(Homaigawd!!! What have I done??!!) Sustaining a relationship / marriage is a lot of hard work. Trust me!! Trying to change your partner is definitely not an option. Looking for a perfect person will take you forever. But learning to accept the other person as-he-is saves you from a lot of heart ache.

AM I WITH THE RIGHT PARTNER?

During a seminar, a woman asked,? How do I know if I am with the right person??

The author then noticed that there was a large man sitting next to her so he said, ?It depends. Is that your partner?? In all seriousness, she answered ?How do you know?? Let me answer this question because the chances are good that it?s weighing on your mind replied the author.

Here?s the answer?

Every relationship has a cycle? In the beginning; you fall in love with your partner. You anticipate their calls, want their touch, and like their idiosyncrasies. Falling in love wasn?t hard. In fact, it was a completely natural and spontaneous experience. You didn?t have to DO anything. That?s why it?s called ?falling? in love.

People in love sometimes say, ?I was swept of my feet.?Picture the expression. It implies that you were just standing there; doing nothing, and then something happened TO YOU.

Falling in love is a passive and spontaneous experience. But after a few months or years of being together, the euphoria of love fades. It?s a natural cycle of EVERY relationship.

Slowly but surely, phone calls become a bother (if they come at all), touch is not always welcome (when it happens), and your spouse?s idiosyncrasies, instead of being cute, drive you nuts. The symptoms of this stage vary with every relationship; you will notice a dramatic difference between the initial stage when you were in love and a much duller or even angry subsequent stage.

At this point, you and/or your partner might start asking, ?Am I with the right person?? And as you reflect on the euphoria of the love you once had, you may begin to desire that experience with someone else. This is when relationships breakdown.

The key to succeeding in a relationship is not finding the right person; it?s learning to love the person you found.

People blame their partners for their unhappiness and look outside for fulfillment. Extramarital fulfillment comes in all shapes and sizes.

Infidelity is the most common. But sometimes people turn to work, a hobby, friendship, excessive TV, or abusive substances. But the answer to this dilemma does NOT lie outside your relationship. It lies within it.

I?m not saying that you couldn?t fall in love with someone else. You could. And TEMPORARILY you?d feel better. But you?d be in the same situation a few years later.

Because:

The key to succeeding in a Relationship is not finding the right person; it?s learning to love the Person you found.

SUSTAINING love is not a passive or spontaneous experience. You have to work on it day in and day out. It takes time, effort, and energy. And most importantly, it demands WISDOM. You have to know WHAT TO DO to make it work. Make no mistake about it.

Love is NOT a mystery. There are specific things you can do (with or without your partner), Just as there are physical laws Of the universe (such as gravity), there are also laws for relationships. If you know how to apply these laws, the results are predictable.

Love is therefore a ?decision?. Not just a feeling.

Remember this always: God determines who walks into your life. It is up to you to decide who you let walk away, who you let stay, and who you refuse to let GO..

Much love.. XOXO

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Source: http://barelysupermommy.com/2013/02/25/1101/

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Golf-Passionate Poulter again fuelled by matchplay energy


By Mark Lamport-Stokes

MARANA, Arizona | Sun Feb 24, 2013 2:07am GMT

MARANA, Arizona Feb 23 (Reuters) - Whether it is the biennial Ryder Cup or the annual WGC-Accenture Match Play Championship, Ian Poulter has always been electrified by the challenge of one-on-one golf.

It has been no different this week at Dove Mountain where the flamboyant Englishman has remained unbeaten after four matches as he bids to replicate his title triumph here three years ago.

"My record in match play is very, very good and I'm just very comfortable going toe-to-toe with somebody," Poulter told reporters after beating American veteran Steve Stricker 3&2 in the quarter-finals on Saturday.

"I'm playing for myself this week. I really enjoy the fun of match play. As good as my record is in Ryder Cup, in some way it doesn't translate into playing just for yourself."

Poulter has been a talismanic force for Europe at the Ryder Cup where he has compiled an overall record of 12-3-0 with his eye-bulging, fist-pumping passion.

Asked to compare the intensity of the Ryder Cup with his focus at the Match Play Championship, Poulter replied: "It's there. It's there. Definitely, it's there. But you can't compare it. It's very difficult.

"In Ryder Cup you've got 50,000 fans, and here you haven't quite got that many fans, so you're not feeding off the crowd, you're just trying to do it yourself.

"You can't get as much adrenaline going as you can in the Ryder Cup, but yet there's still intense moments out there on the golf course to switch your brain on," the Briton said after improving his Match Play Championship (win-loss) record to 22-9.

CLUTCH PUTTS

Poulter made several clutch putts and one chip-in on the way to his victory over Stricker as he set up a mouth-watering showdown with champion Hunter Mahan in Sunday's semi-finals.

Long regarded as one of the best putters in the game, Poulter believes his all-round form this week very close to that in 2010 when he outplayed fellow Briton Paul Casey 4&2 in the Match Play Championship final.

"I feel as good," said the ultra-confident Englishman, a 12-times winner on the European Tour. "I feel I'm a better player today than what I was in 2010.

"I feel more equipped than what I was in 2010. I feel like I'm rolling the ball as good as I was certainly in 2010."

Poulter's decision to take six weeks off competitive golf since he tied for ninth at the PGA Tour's season-opening Hyundai Tournament of Champions in Hawaii has been especially beneficial this week.

"I couldn't be any more ready to play golf," he smiled. "Albeit I never played a round of golf for the last four weeks of my six weeks off, I didn't play one round, I didn't play one hole, so I came here very, very well practised.

"I had a lot of range work to do, so I've done that, and it's transferred from the range to the golf course this week. It was a case of, yes, I have had six weeks off and I just need to get that buzz going.

"I feel really good. It will be more mentally tiring than anything else over the next couple of rounds, so hopefully I can pull on what I've done in the last six weeks ... and be really strong tomorrow."

The two semi-finals will be followed by the championship final at Dove Mountain on Sunday. (Editing by Greg Stutchbury)

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Source: http://www.thespainforum.com/f234/golf-passionate-poulter-fuelled-matchplay-energy-414175/

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Right Wing Rages Uncontrollably at Michelle Obama: "Someone Put a Bullet in That Fat Pig" (Little green footballs)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/287328761?client_source=feed&format=rss

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NFL Combine: Who stole the show? - Browns - Ohio

Arkansas-Pine Bluff OT Terron Armstead

How he did it: Armstead, who is 6-foot-5 and weighs 306 pounds, ran the 40-yard dash in 4.71 seconds, the best time by an offensive lineman since at least 2006, according to the NFL. A standout at the East-West Shrine Game, Armstead also finished first among linemen in the vertical jump (34.5 inches), tied for fourth in the broad jump (9-4), tied for eighth in the bench press (31 reps of 225 pounds) and tied for 13th in the three-cone drill (7.62 seconds).

Armstead said he was recruited by Missouri, Kansas and Kansas State, but ended up at Pine Bluff because he didn?t get the ACT score he needed until after signing day. He also competes in track at Pine Bluff, and said 61 feet, 5 inches in the shot put is his personal best there.

?I?ve been blessed with a unique skill set. I?m extremely light on my feet for a big guy,? he said last week. ?It?s a blessing.?

? Marla Ridenour

Source: http://feedproxy.google.com/~r/ObrNewswire/~3/fzeqlU-y5ko/nfl-combine-who-stole-the-show-1.375841

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Survey shows China manufacturing at 4-month low

BEIJING (AP) -- A survey shows China's manufacturing activity this month has declined to a four-month low in a reminder of possible threats to its shaky economic recovery.

HSBC Corp. said Monday the preliminary version of its purchasing managers index for February fell to 50.4 on a 100-point scale on which numbers above 50 show activity expanding. That was down from January's 52.3.

Growth in the world's second-largest economy rebounded in the final quarter of 2012 but analysts say a recovery will be gradual and could be vulnerable if trade or investment decline.

HSBC said its survey found export orders decreased while output and overall orders grew at a slower rate.

HSBC economist Hongbin Qu says in a statement that "the Chinese economy is still on track for a gradual recovery."

Source: http://news.yahoo.com/survey-shows-china-manufacturing-4-024024106.html

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UK press: Host of upcoming G8 summit encouraging Obama and others to leave their spouses at home (Michellemalkin)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/286896770?client_source=feed&format=rss

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