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Friday, October 12, 2012
Ex-head of military team in Libya: security weak - 8 News NOW
By LARRY MARGASAK and MATTHEW LEE
Associated Press
Associated Press
WASHINGTON (AP) - Four weeks before the election, Republicans used a politically charged House hearing to confront State Department officials about security at the U.S. Consulate in Libya and assail the Obama administration's early response to the killing of the ambassador and three other Americans there.
GOP lawmakers refused to accept the department's explanation Wednesday that protection judged adequate for the threat was overwhelmed by an unprecedented assault in Benghazi on the 11th anniversary of the Sept. 11 terror attacks.
They also rejected Undersecretary of State Patrick Kennedy's explanation that officials were relying on the best intelligence available in characterizing the attack afterward as stemming from a protest over an anti-Islam Internet video rather than a deliberate, planned act of terrorism.
A top State official acknowledged she had declined to approve more U.S. security as violence in Benghazi spiked, saying the department wanted to train Libyans to protect the consulate.
"I made the best decisions I could with the information I had," said Charlene R. Lamb, a deputy assistant secretary for diplomatic security.
Regardless of allegations of blame, there is no dispute over the tragic result. U.S. Ambassador Chris Stevens and three other Americans - including two former Navy SEALs - were killed in what administration officials now describe as an act of terrorism.
In statements immediately after the attack, neither President Barack Obama nor Secretary of State Hillary Rodham Clinton mentioned terrorism. And both gave credence to the notion that the attack was related to protests about the privately made anti-Islam video.
"Some have sought to justify this vicious behavior as a response to inflammatory material posted on the Internet," Clinton said on the night of the attack. "The United States deplores any intentional effort to denigrate the religious beliefs of others. Our commitment to religious tolerance goes back to the very beginning of our nation. But let me be clear: There is never any justification for violent acts of this kind."
Five days later, U.N. Ambassador Susan Rice said her best information at the time was that the attack stemmed from a protest that became violent.
President Barack Obama, asked on ABC about the changing accounts of what instigated the attack, said the information was evolving.
"As information came in, information was put out, the information may not have always been right the first time," he said. "These are people I know, and if there is something to be fixed, it will get fixed."
White House spokesman Jay Carney told reporters Wednesday that in hindsight "there is no question that the security was not enough to prevent that tragedy from happening. There were four Americans killed."
Democrats on the House Oversight and Government Reform Committee tried to blame Republicans for cutting more than $300 million in diplomatic security funds worldwide.
"The fact is that, since 2011, the House has cut embassy security by hundreds of millions of dollars below the amounts requested by the president," said Maryland Rep. Elijah Cummings, the committee's senior Democrat.
Lamb, the official in charge of protecting U.S. embassies and consulates, told the committee, "We had the correct number of assets in Benghazi at the time of 9/11."
Rep. Dan Burton, R-Ind., asked Lamb if she turned down requests for more security in Benghazi.
"Yes sir, I said personally I would not support it," she replied. "We were training local Libyans and army men" to provide security, a policy in force at U.S. diplomatic facilities around the world.
Committee Chairman Darrell Issa, R-Calif., retorted there was "as much as 30 percent turnover in the people you were training."
Eric Nordstrom, who was the top security official in Libya earlier this year, testified he was criticized for seeking more security. "There was no plan and it was hoped it would get better," he said.
Nordstrom told the committee that conversations he had with people in Washington led him to believe that it was "abundantly clear we were not going to get resources until the aftermath of an incident. How thin does the ice have to get before someone falls through?"
He said he was so exasperated at one point he told a colleague that "for me the Taliban is on the inside of the building."
Lt. Col. Andrew Wood, who headed a 16-member military force in Libya, disputed State Department officials who said the special operations troops were replaced by people with the same skill sets.
The skills of his troops were "way above the skill level of local (forces) armed with a pistol," Wood said, adding he was he was frustrated that pleas for more security were not met.
"We were fighting a losing battle, we weren't even allowed to keep what we had," he testified.
Nordstrom acknowledged in response to a question from Rep. Jason Chaffetz, R-Utah, that while the State Department was refusing more security, his and others' pay was increased because he was serving in such a dangerous area.
Kennedy defended Rice for her comments indicating the attack was a protest gone awry.
"If any administration official, including any career official, were on television on Sunday, Sept. 16, they would have said what Ambassador Rice said," he said. "The information she had at that point from the intelligence community is the same that I had at that point. As time went on, additional information became available. Clearly, we know more today than we did on the Sunday after the attack."
Kennedy, a four-decade veteran of the Foreign Service, said the department uses the best information from people on the ground at diplomatic posts around the world as well as experts in Washington in assessing risk and allocating security resources.
"The assault that occurred on the evening of Sept. 11, however, was an unprecedented attack by dozens of heavily armed men," he said.
Meanwhile, Obama's chief counterterrorism adviser, John Brennan, met Wednesday with Libyan President Mohamed Magariaf and other officials in Tripoli on ways Libya can better help the U.S. track down those responsible for the deaths at the consulate.
Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Source: http://www.8newsnow.com/story/19779886/state-dept-description-of-attack-in-sync-with-gop
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Thursday, October 11, 2012
bologna tori: Travel Leisure City Guides and Information: Go to
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New studies could result in better treatments for epilepsy, behavioral disorders
ScienceDaily (Oct. 11, 2012) ? Three studies conducted as part of Wayne State University's Systems Biology of Epilepsy Project (SBEP) could result in new types of treatment for the disease and, as a bonus, for behavioral disorders as well.
The SBEP started out with funds from the President's Research Enhancement Fund and spanned neurology, neuroscience, genetics and computational biology. It since has been supported by multiple National Institutes of Health-funded grants aimed at identifying the underlying causes of epilepsy, and it is uniquely integrated within the Comprehensive Epilepsy Program at the Wayne State School of Medicine and the Detroit Medical Center.
Under the guidance of Jeffrey Loeb, M.D., Ph.D., associate director of the Center for Molecular Medicine and Genetics (CMMG) and professor of neurology, the project brings together researchers from different fields to create an interdisciplinary research program that targets the complex disease. The multifaceted program at Wayne State is like no other in the world, officials say, with two primary goals: improving clinical care and creating novel strategies for diagnosis and treatment of patients with epilepsy.
The three studies were published in high-impact journals and use human brain tissue research to identify new targets for drug development, generate a new animal model and identify a new class of drugs to treat the disease. In the first study, "Layer-Specific CREB Target Gene Induction in Human Neocortical Epilepsy," published recently in the Journal of Neuroscience, donated human brain samples were probed to identify 137 genes strongly associated with epileptic seizures.
Researchers then showed that the most common pathway is activated in very specific layers of the cortex, and that it's associated with increased numbers of synapses in those areas. Because epilepsy is a disease of abnormal neuronal synchrony, the finding could explain why some brain regions produce clinical seizures.
"Higher density of synapses may explain how abnormal epileptic discharges, or spikes, are formed, and in what layer," Loeb said, adding that localizing the exact layer of the brain in which that process occurs is useful both for understanding the mechanism and for developing therapeutics.
The first study, which identified a new drug target for epilepsy, precipitated a second study that has found such a drug.
In the second study, "Electrical, Molecular and Behavioral Effects of Interictal Spiking in the Rat," published recently in Neurobiology of Disease, SBEP researchers found that the same brain layers in the rat are activated as in the human tissues and searched for a drug to target those layers. In fact, the first drug they tried, a compound called SL327 that has been used in nonhuman subjects to understand how memory works, "worked like a dream," Loeb said. "SL327 prevented spiking in rat brains," he said, "which not only prevented seizures, but led to more normal behaviors as well."
That finding led to collaborations between Loeb's lab and Nash Boutros, M.D., professor of psychiatry and behavioral neurosciences, and the Belgian drug company UCB.
"Whereas animals that developed epileptic spiking became hyperactive, those treated with the drug and had less spiking in their brains were more like normal animals," Loeb said. "Now whenever we screen for drugs for epilepsy, we look at behavior as well as epileptic activity."
Noting that many seizure medicines currently are used to treat various psychiatric disorders, Loeb said the SBEP team's latest round of work marks a "nice crossover" between psychiatry and neurology in the field of drugs related to epilepsy.
In the third study, just published in Genetics, researchers say they have found "fascinating interrelationships" between "junk" long noncoding RNA and normal RNA that are regulated by human brain activity. That work has the potential to be translated into new genetic treatments for epilepsy.
"This study shows how the human brain deals with half of the human genome in its most important function, electrical activity, using human brain tissue from patients with epilepsy to understand the basic molecular processes of how the brain works, and what's unique about human brains compared to the brains of less-developed species," Loeb said.
The third study, titled "Activity-Dependent Human Brain Coding/Noncoding Gene Regulatory Networks," is a collaborative effort between Loeb's lab and Leonard Lipovich, Ph.D., assistant professor of neurology and molecular medicine and genetics. It found that certain genes and their noncoding counterparts (which some researchers have called "junk") are co-regulated, or turned on at the same time, with brain activity.
"This tells us that some of these noncoding genes may actually have functions in brain activity," Loeb said. "In some, turning one on turns another one off. Some are regulatory and can be used to control plasticity genes -- which are involved in memory, learning and behavior -- with one of these novel, noncoding RNA genes."
The synergy exhibited by the three studies, Loeb said, is testimony to the multidisciplinary nature of Wayne State's systems biology platform, partly developed with a remarkable three-dimensional database created in cooperation with Farshad Fotouhi, Ph.D., dean of the College of Engineering, and Jing Hua, Ph.D., associate professor of computer science.
"SBEP is a cross-campus endeavor," Loeb said. "These studies are the fruits of the labor of this consortium and only exist at WSU. The next steps will be translating these exciting findings into new treatments to prevent or even cure patients with epilepsy and other psychiatric disorders."
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The above story is reprinted from materials provided by Wayne State University - Office of the Vice President for Research, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal References:
- Thomas L. Beaumont, Bin Yao, Aashit Shah, Gregory Kapatos and Jeffrey A. Loeb. Layer-Specific CREB Target Gene Induction in Human Neocortical Epilepsy. Journal of Neuroscience, 2012 DOI: 10.1523/%u200BJNEUROSCI.3408-12.2012
- Daniel T. Barkmeier, Danielle Senador, Karine Leclercq, Darshan Pai, Jing Hua, Nash N. Boutros, Rafal M. Kaminski, Jeffrey A. Loeb. Electrical, molecular and behavioral effects of interictal spiking in the rat. Neurobiology of Disease, 2012; 47 (1): 92 DOI: 10.1016/j.nbd.2012.03.026
- L. Lipovich, F. Dachet, J. Cai, S. Bagla, K. Balan, H. Jia, J. A. Loeb. Activity-dependent Human Brain Coding/Non-coding Gene Regulatory Networks. Genetics, 2012; DOI: 10.1534/genetics.112.145128
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/IyZ_kYgiFAc/121011162156.htm
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Ask the Addict: Orange Lingerie?
A Flo Foxworthy Design
Today?s ?Ask the Addict? question comes from a TLA Tumblr follower, Madelinne, who writes:
?You posted the most gorgeous orange corset (Editor?s Note: By Flo Foxworthy, shown above) ? which got me on the hunt for orange and pumpkin colored lingerie. Any ideas? My google search was fairly fruitless.?
Even though it?s Halloween season, I hadn?t really thought about orange lingerie before now?but thanks for the suggestion! Wearing something bright orange is a great way for people to indulge in the season (Autumn and Halloween) without necessarily going the ?Sexy Costume? route. Below is a quick round-up of what I found. As always, click the photo to view the product directly.
Anthropologie Lacy Color Pop Panty ? $16.00
Hips & Curves Stretch Lace Chemise ? $24.95 (sale price)
Hanky Panky ?Screaming Orange? Boyshort ? $29.00
TEN High Waisted Brief ? $45.00
TOMgirl Comfort Bra ? $47.00
Love Claudette Dessous Sucre ? $78.00 (both pieces)
Zinke Bralet and Panty ? $92.00 (both pieces)
Cosabella ?Never Say Never? Chemise ? $117.50
Princess Tam-Tam ?Tutu? Bra & Brief ? $127.00
Marlies Dekkers ?Kissing You? Bra & Brief ? $158.00 (both pieces)
HoneyCooler Handmade Pumpkin Ribbon Cincher ? $165.00
Source: http://www.thelingerieaddict.com/2012/10/ask-the-addict-orange-lingerie.html
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Hyped Genetically Modified Maize Study Faces Growing Scrutiny
Image: nysm.nysed.gov/
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Showcasing more than fifty of the most provocative, original, and significant online essays from 2011, The Best Science Writing Online 2012 will change the way...
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From Nature magazine
The storm of scientific criticism over claims that a genetically modified (GM) maize causes severe disease in rats shows no signs of abating.
Gilles-Eric S?ralini, a molecular biologist at the University of Caen, France, is under intense pressure to report the full data behind his team?s finding that rats fed for two years with Monsanto?s glyphosate-resistant NK603 maize (corn) developed many more tumours and died earlier than controls (see Nature 489, 484; 2012). The study, run in collaboration with the Paris-based Committee for Research and Independent Information on Genetic Engineering (CRIIGEN), also found that rats developed tumours when their drinking water was spiked with glyphosate, the herbicide that is used with the GM maize. The findings have had a huge public impact in Europe, empowering those opposed more broadly to GM foods, and leading some politicians to call for tighter regulations or outright bans of the maize.
Last week, the European Food Safety Authority (EFSA) in Parma, Italy, and Germany?s Federal Institute for Risk Assessment (BfR) in Berlin both issued initial assessments slamming the paper, bluntly asserting that its conclusions are not supported by the data presented. ?The design, reporting and analysis of the study, as outlined in the paper, are inadequate,? says the EFSA in a press release, adding that the paper is ?of insufficient scientific quality to be considered as valid for risk assessment?.
The biggest criticism from both reviews is that S?ralini and his team used only ten rats of each sex in their treatment groups. That is a similar number of rats per group to that used in most previous toxicity tests of GM foods, including Missouri-based Monsanto?s own tests of NK603 maize. Such regulatory tests monitor rats for 90 days, and guidelines from the Organisation for Economic Co-operation and Development (OECD) state that ten rats of each sex per group over that time span is sufficient because the rats are relatively young. But S?ralini?s study was over two years ? almost a rat?s lifespan ? and for tests of this duration, the OECD recommends at least 20 rats of each sex per group for chemical-toxicity studies, and at least 50 for carcinogenicity studies.
Moreover, the study used Sprague-Dawley rats, which both reviews note are prone to developing spontaneous tumours. Data provided to Nature by Harlan Laboratories, which supplied the rats in the study, show that only one-third of males, and less than one-half of females, live to 104 weeks. By comparison, its Han Wistar rats have greater than 70% survival at 104 weeks, and fewer tumours. OECD guidelines state that for two-year experiments, rats should have a survival rate of at least 50% at 104 weeks. If they do not, each treatment group should include even more animals ? 65 or more of each sex.
?There is a high probability that the findings in relation to the tumour incidence are due to chance, given the low number of animals and the spontaneous occurrence of tumours in Sprague-Dawley rats,? concludes the EFSA report. In response to the EFSA?s assessment, the European Federation of Biotechnology ? an umbrella body in Barcelona, Spain, that represents biotech researchers, institutes and companies across Europe ? called for the study to be retracted, describing its publication as a ?dangerous case of failure of the peer-review system?.
S?ralini argues that a battery of observations in the study reinforces his tumour-incidence and mortality claims. ?Of course, this should be replicated by others, but we believe in these results,? he says. He agrees that more rats would have boosted his study?s statistical power, but says that he did not design the experiment to show differences in tumour incidences, because he was not expecting to find any ? no previous tests on GM foods had suggested a cancer risk.
Source: http://rss.sciam.com/click.phdo?i=fed06d76849a8702a6c08cb4f36b023e
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It's Time to Redefine Retirement with Villa | Villa Communities
What did you imagine your retirement to be? For some it?s full of travel, for others it?s about spending time with family and friends or even volunteering with newfound purpose. Whatever you imagined your retirement to be, one thing is for sure, it doesn?t involve work! Retirement is a time to do the things you always wanted to do ? even if that means doing nothing at all!
The truth is, when it comes to retirement these days, the possibilities are wide open. Unlike generations past, today?s retirees are trading shuffleboard, bingo halls and a closet full of cardigans for gym workouts, continuing education and neighborly gatherings ? especially if you?re a retiree at the Villas at Yorktown and the Villas at Five Forks.
?The vision behind Villa Development was always to be a place where retirees can come to trade-in the burdens of maintaining a big home and instead enjoy the latest amenities of a brand new home in a maintenance-free community,? affirmed Shelia Byers, Vice President of Marketing for Villa Development. ?Most of our residents live fuller lives now than before simply because they have the freedom and time to do it!?
So how exactly does Villa help you redefine your retirement? For starters, Villas Communities are maintenance-free. That means you have professional landscapers year round who cut the grass, maintain your yard, shovel snow from the sidewalks and rake leaves in the fall. When that lamppost light outside burns out, the professionals at Villa handle that, too.
There?s also the Community Clubhouse, the hub of activity for every Villa Community where residents gather to catch up, work out, play pool, go for a swim or even reserve the space for special functions. The Villas at Yorktown is also conveniently located near the bustling Yorktown River Walk, filled with unique shops, the river beach and local seafood dining. While the Villas at Five Forks is located within minutes of historic Williamsburg with its many attractions as well as William & Mary?s Christopher Wren Association, offering a variety of opportunities for continuing education.
?It?s about more than a beautiful new home,? stated Byers. ?Villas offer residents an exceptional way of life where anything is possible.?
Speaking of exceptional homes, Villas at Yorktown and Villas at Five Forks recently unveiled their newest Designer?s Showplace Model Homes complete with an upgraded spa bath in the master with a walk-in shower as well as a newly remodeled kitchen featuring redesigned cabinets and space-saving technology. The one-level spacious floor plans of the Villas at Yorktown and Five Forks also feature attached two-car garages, gourmet kitchens and glass verandas. But Villa goes beyond outstanding design to also ensure your home is built with nothing less than the national brands you trust. That?s because Villa is part of the Epcon Communities Family, found in more than 30 states, and as such, Villa can leverage Epcon?s national buying power and pass on the savings to you right here in Virginia. So brands like Mohawk, Sherwin Williams, Moen, Kenmore, Merilatt, Lennox and more are used throughout each Villa home giving residents more of the top brands they want for less!
Quality is a signature of every Villa home inside and out as seen in Villa?s Five Star Performance building practices to ensure tremendous energy savings. Villa even follows a three-stage quality assurance walk-thru of your home ? with the builder ? in order to give you the ultimate peace of mind.
So whether you?re nearing retirement or you?re already at that great milestone, you owe it to yourself to pay a visit to The Villas at Yorktown and The Villas at Five Forks. From the communities themselves to the details in your very own Villa home, it?s safe to say that the possibilities for your retirement are wide open and Villa will make sure it is the absolute best it can be.
Source: http://www.villa-communities.com/2012/10/it%E2%80%99s-time-to-redefine-retirement-with-villa/
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